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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8727cd2d4b94023f969bda4c9f63f7f8a83ffdfffe2563853879e940da1aef' 
  AND token = 'aSbZtIGG/VJhIfQ72/UMVA2AQ/DBBXhOQn0UgYfiG3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}