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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53cda57459f3756784a99190c3eaf6e34ff369f4b504f60ff226e0270f115792' 
  AND token = 'Xb6wSNn+1F7+bvWunGfKAHBCiXZ4Z1tcmfZtzbnWl1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}