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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5012b4f6a981424e1475cc33a5e57314556cd173b2d66e45fd63d8c17147cf60' 
  AND token = '5kuT8bfT1N92s91N3H9+tw+ykLvTVWk/3oKKrgUyvmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}