SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f745dc0c985d5325934c0dbcefeef689b03b248d6be7797c69cc6b54f726733' 
  AND token = 'IEKoN/r7O21/ikvFqh6fSk85rRB6hQLMDbHBhZsTBrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}