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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a858edb687045309da3fb0b2b3d80d561de381d35b3800fb600372cadd04ce0' 
  AND token = 'BX7m8hF3Cztzek+Hq23w+AKBOGrjhihKc4Nw3CTqmIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}