SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9e2f8e43d09471d522f46fac38c3383cdbe917ebd99562f840a480a85e006d' 
  AND token = 'KXUda+sxboVEAdst+glIY6CUFMCGpmuwlN+0pCLOPoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}