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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12ef525b7396a6c8c9c35799c4030650b4dfa1a6a2e726710f42f4bc5b2bd80' 
  AND token = 'SUSfe42ZRglRuI7sbdMd9nJb/6NYf7Vk4siKMZjgkeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}