SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e829f3158278f509f335fa2a1fb0754852566ce539c1b28a4f86f330de26b7d7' 
  AND token = 'A2feKxtvWJ6LkbgSNEXhZw2rUfvRIjb8cwRNVlTfsfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}