SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d87a7f4ba897f1710e584e26e6fb428ac927a85fa35550975f45c47f5e9224' 
  AND token = 'MIwy+BaJ2D0e/hbpXwETT9bwjkCxH9q7bfdVgN26J7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}