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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36440128bd49b721d1be5346f79c6242a938b431e753e6abcca13d95e922d7a3' 
  AND token = '/durexV790uQAK/GQUubPb+N2TcCvJfBDjDT0yWjY+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}