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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f44ff775e4872f49a84d84e1934df4b45b12d3ab5eeb808fd7e203a473b733' 
  AND token = '3A9r5OAnvhfRHQ7GSPagCRn0dKOEe6xwEDX9VC82Cek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}