SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59cc665b2d2481ae48cf7d2943b269ac977e1bd9cbd96e6698bd0579ffa0782' 
  AND token = 's5fMnDchfPEpfS19Yq+oeWsYB2bd+bF12I1Wyg8FZYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}