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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10eeddc54372e917765fb558ba2d089b7e4d1d2c69198ef37bc77c6773669533' 
  AND token = 'tSFaejqoaOrdvpW53P0W4fx4vE7ny/BRri0XHvd6LgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}