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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1e8ee38d73289dae35a07cf35f2f84a5072fc9e229ac3150ad408c2de14fe1' 
  AND token = '2VCVFROY8mqvIzRlUKPC0YdrZj6xUvDL34Q3RxeoXWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}