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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69ff793c785355f607ac0851bbcfd82ec610d08454de06f9075c9a023a5bb620' 
  AND token = 'ANduQvCZ0/8xijLbHJsjqyM+EBiwNk8j4OIMdgSu4OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}