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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f2ab84d2554096a891343834e49770f1e7935828c4f8d6de11afa8139be2c3' 
  AND token = 'R3N0VbfK11NOcIqu5zPWTJ0D9S7RAZpCMvsoSmRvLb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}