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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d1aebc674ee18aaf8ad46c0132855399eeb57f550a9dc48a94a30858c45966' 
  AND token = 'Diy2oY/1aFejjzR3ZND8jtYUsQwlOdB2xfNZo35c7hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}