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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27155c2e437e1ff8a15589b8af8c22a73bab0c20a757d0b50e0e74303aef88a0' 
  AND token = 'eBFvOn7sN5UvNT2RmDDQXeT72KXoii5kMnz8b698f6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}