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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3004c1d0b411f56537bef5c1faf80aac61e0f29fead5f4506c184d08fa0408bb' 
  AND token = '0/lICYW8vXadcEzZLXR88Tc6PbUI+hNzAbADRkpCQNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}