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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8af7c1383cd5f828eb62b68b08c158c05a29a9f4b122b6b5eeccffe1e8343c3' 
  AND token = '/6q0yQNlcc+/2d0w4PZ8WcIP+2PDzyssTC7HzhPhbsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}