SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58f44f4c8847e6dc346f284a74ae01d91c5030d13d5ee42c9160582a1e617949' 
  AND token = 'Qqa+VjiJrUPfNyKovYC0pzn+OO2BqoinV+5dDA10Kvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}