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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7580a50109823021382b96d70f8e9ef6ee35d3b2bd6fb66feeb5df5a749560af' 
  AND token = 'chqi1ft/LLQVihvTgDd4xDUXhJqq4n9YMNjcf6pyetg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}