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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e17f227867caad063b216325b9c37d1a0555097bf65bb953f60383cad5f3df91' 
  AND token = 'xRPQAionoK7KkPELAQ/L9t7dZIHKzJsD5wLdoHjJRa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}