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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2600d1d86a65fb99f2f985e7f84b32a553e1d2c3ec9cd373e8969e6e57327323' 
  AND token = 'ZEvinWmRBVCaZkc89lMFw4cvBOxQCeW7uE1zETohrlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}