SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd216f3c41d45b88b228b70afb21f47d7dfe590d65ca97f788f46cba561d3705' 
  AND token = 'If/lfT9Z27rIHd6j+FeN975s0z30lomJAzpEyv+afzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}