SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e4f9386517f3677a36efacb1e0d00e650aaba3d81a834ba445805c98615555' 
  AND token = '2W3XMFGp3artpPFdguC/OcugsNzF22w6fot/6ZYFeKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}