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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726d9a72ad5e15e287a831dc59d3fb7eb211ad02fd7767e619d0c4ac052c1079' 
  AND token = '5XIR9cuuKipZ+eGOeqVgaNg2KH0gzezUVMohVBWfS8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}