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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69ed9b207562692a255e4a035f11b22e0688a156aa9322a90cbc36351eca9857' 
  AND token = '8UO00MjAbsvUfBBvUYi1DvHCZJeOG/IbvyWMLqZ/tWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}