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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db81d6b3629f00c31b4309dc1808f690de2383cddc815060f00d6f2bfb5f6e9c' 
  AND token = 'PIPKME7zLgcLZaiGwa4xo1VXCP7AAA+wcTaWcw2ZCG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}