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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6209282334c00ab770f0a8443fec25d6f77cdc12f785820b2279b962f64897f' 
  AND token = 'U59hPyP+6T+hLeuXvAJMyY2VE8JnjxyBVqo33269pVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}