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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212a61eedeb7b52c6a3ce461e1fbe167d85d2397e729cbd5580553027a33426a' 
  AND token = '3mCkhfwYyZf2BTkYyYVhbyhTJ/BzEWtHFgThTC8Wt1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}