SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f278c230c75d803e1ce60a192c2e4383e7f85d9e15e96e5bfbe167a6d8dea73' 
  AND token = '10VTou2FNr9pcqYFjkuo0WVcFr2JKuYV4M4SWABcnNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}