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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d4d970864e7253598d167425b565b1ca80e44769a60c64a28d5057a2810329' 
  AND token = 'VMWpHZoZ84+sIwL8HjDoj6W5zzMSJ8EQUImFBfbRMY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}