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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5cbe321e2c85dab46cb260691cd0648b3246bfb29a2ad9106461506eaec8a8f' 
  AND token = 'RpKa67p72+jtypOTfNBXgOn33jMVaKkwC2lo677CNy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}