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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f25e765e1c754884da3c7e5afd8384b7688195ff01faae2e4c831d2abb97a21' 
  AND token = 'wWkWe7c1d/Xkj7wjM8EvYh/O4ShDu6JRbITPZiAjAws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}