SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caecdcaede9f3f7a732fc8fdf39b330504e94d02c6eafe27092db5c869bb1188' 
  AND token = 'bRGgd0vSuS0Ym/V4mTGJeO5Jqp6cpvFHh3xSR53gFCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}