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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2001474d1bc436b2212abe5b18765241a72c39533882854f24fe1841bb34c869' 
  AND token = '+FLacuOr0vkEf6SkhMHEPEc3MDGvw2IHolc280kK2uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}