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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8305f139ed47540c891c722ee258125faec78f50acf5d1aa07fb84f19833f23c' 
  AND token = 'WuaNzxAH3AW2GhTcUQ5Bl/V5UNg8xf8BIreUWSkuc0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00106

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}