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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e1494264622e8f24006696dc848d866365234519ded4b7b24a46092caf0054' 
  AND token = 'b+dEzJr2S3jWw0Wuv1StSMow5CJbTuyU3wLPbjGmwWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}