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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efa3d1a727441cee5f0f294d76c2c80bc664bb80ab73d8205cecf3d141ab137' 
  AND token = 'IOC1WOB5tbtTOTMzy56+JrvwnYBdpEe/BXztiarJw0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}