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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374ca038ec0de780740cc8f97c7fabb729bddb091ba66acb1a9f0a311e50b626' 
  AND token = 'Pt3nmTy9UyCLIHctSUQ8SjxKQR2tp1MtIt0zAohU4cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}