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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4be4a4e8be57f753f12c1092c08111784fdb45d2d99eaa28f4c22d0489bc94' 
  AND token = 'LjuCT19Ezp2I3yod2Hl65dPmJ+zRRKG+u5QUg9lZ2cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}