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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d08325678f772659098951a70cfc529d948f9e827b322b762b98e892a3c417e' 
  AND token = 'me0MckZO+EjRZil6a8CpH+TxVGGIBTw9BNF7gALdAxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}