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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a67ae11740e0473c66537a68cc95ac157fc1341034a9553bd7c2dafed755334' 
  AND token = 'OjVYDmlgEGz0/KTPvfaXIwUpxMk1bNtH1m/Xzl+cFkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}