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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c54689d23f9980bdd2dfba78faa399d3601e5ace46435441d0425a0b60c101' 
  AND token = 'i0vN/p4khlFHh2TtDkmv1o4m5zw+TFK2rxuFAb561qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}