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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47a027fa1e47d8b2438ba6ef406afe15d93aa77a2c336a507624f382b15e221f' 
  AND token = 'OOcha6wGeoPfs22PLHQwmiRIpO+4Kl69xRGY0ILmpwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}