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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b106c8a721b538dedf4c9461712a4ded80cdd728da1dac94e8e2752c3981a1' 
  AND token = '8le7NrqjI+OUtxu3vRma+auui+4C7bQNsBw2rDwRizM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}