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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c377f2f9645cef604b3d378472667a458a9859b77acbcd594605c8468db7638' 
  AND token = 'MheBdXof/m9U+ryD57U3qhx7R3IdayeN7PDJspNHMFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}