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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49961e3e8f94bb95825b040d48c459036023748c4cb94d34b167f4e8d2c569e1' 
  AND token = '267lt3lbbHOJAH6pZhgsxd7Mgdh2KnclMsXaaTfW2mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}