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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1b87ffefbe5f47706abeb0aa0d0ad105e8f6d882f80429aea2f9d357ac43c6' 
  AND token = 'A2Y13bmNCDv7rGMGB885AwmD1jtlBrQJ5+DrB/vvmYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}